Systematic evaluation of serum and plasma collection on the endogenous metabolome

Papers of special note have been highlighted as: • of interest; •• of considerable interest

References

• 1 Xu J, Chen Y, Zhang R et al. Global and targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkers. Mol. Cell. Proteomics 12(5), 1306–1318 (2013).
  Medline CASGoogle Scholar
• 2 Pan Z, Gu H, Talaty N et al. Principal component analysis of urine metabolites detected by NMR and DESI–MS in patients with inborn errors of metabolism. Anal. Bioanal. Chem. 387(2), 539–549 (2007).
  Medline CASGoogle Scholar
• 3 Fava F, Lovegrove JA, Gitau R et al. The gut microbiota and lipid metabolism: implications for human health and coronary heart disease. Curr. Med. Chem. 13(25), 3005–3021 (2006).
  Medline CASGoogle Scholar
• 4 Donald GR, Michael DR, J DB. Metabonomics in pharmaceutical discovery and development. J. Proteome Res. 6(2), 526–539 (2007).
  MedlineGoogle Scholar
• 5 Schnackenberg LK, Beger RD. Monitoring the health to disease continuum with global metabolic profiling and systems biology. Pharmacogenomics 7(7), 1077–1086 (2006).
  Medline CASGoogle Scholar
• 6 Rezzi S, Ramadan Z, Martin FP. Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals. J. Proteome Res. 6(11), 4469–4477 (2007).
  Medline CASGoogle Scholar
• 7 Issaq HJ, Xiao Z, Veenstra TD. Serum and plasma proteomics. Chem. Rev. 107(8), 3601–3620 (2007).
  Medline CASGoogle Scholar
• 8 Kronenberg F, Trenkwalder E, Kronenberg MF, König P, Utermann G, Dieplinger H. Influence of hematocrit on the measurement of lipoproteins demonstrated by an example of lipoprotein(a). Kidney Int. 54, 1385–1389 (1998).
  Medline CASGoogle Scholar
• 9 Tripisciano C, Leistner A, Linsberger I, Leistner A, Falkenhagen D, Weber V. Effect of anticoagulation with citrate versus heparin on the adsorption of coagulation factors to blood purification resins with different charge. Biomacromolecules 13(2), 484–488 (2012).
  Medline CASGoogle Scholar
• 10 Yu Z, Kastenmüller G, He Y et al. Differences between human plasma and serum profiles. PLoS ONE 6(7), e21230 (2011).
  Medline CASGoogle Scholar
• 11 Barri T, Dragsted LO. UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant. Anal. Chim. Acta 768, 118–128 (2013). •• Compared the differences on metabolomes of serum, heparin plasma, EDTA plasma and citrate plasma based on MS.
  Medline CASGoogle Scholar
• 12 Skov K, Hadrup N, Smedsgaard J, Frandsen H. LC–MS analysis of the plasma metabolome – a novel sample preparation strategy. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. doi:10.1016/j.jchromb.2014.11.033 (2015) (Epub ahead of print).
  MedlineGoogle Scholar
• 13 Basu D, Kulkarni R. Overview of blood components and their preparation. Indian J. Anaesth. 58(5), 529–537 (2014).
  Medline CASGoogle Scholar
• 14 Michopoulos F, Lai L, Gika H, Theodoridis G, Wilson I. UPLC–MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction. J. Proteome Res. 8(4), 2114–2121 (2009).
  Medline CASGoogle Scholar
• 15 Tulipani S, Llorach R, Urpi-Sarda M, Andres-Lacueva C. Comparative analysis of sample preparation methods to handle the complexity of the blood fluid metabolome: when less is more. Anal. Chem. 85(1), 341–348 (2013).
  Medline CASGoogle Scholar
• 16 Yang W, Chen Y, Xi C et al. Liquid chromatography-tandem mass spectrometry-based plasma metabonomics delineate the effect of metabolites’ stability on reliability of potential biomarkers. Anal. Chem. 85(5), 2606–2610 (2013).
  Medline CASGoogle Scholar
• 17 Yan R, Colantonio D, Wong PY, Chen Y. Suitability of Becton Dickinson Vacutainer rapid serum tube for collecting and storing blood samples for antibiotic and anticonvulsant drug monitoring. J. Clin. Pathol. 67(9), 807–810 (2014).
  MedlineGoogle Scholar
• 18 Gislefoss RE, Grimsrud TK, Mørkrid L. Stability of selected serum hormones and lipids after long-term storage in the Janus Serum Bank. Clin. Biochem. 48(6), 364–369 (2015).
  Medline CASGoogle Scholar
• 19 Tammen H, Schulte I, Hess R et al. Peptidomic analysis of human blood specimens: comparison between plasma specimens and serum by differential peptide display. Proteomics 5(13), 3414–3422 (2005).
  Medline CASGoogle Scholar
• 20 Hsieh SY, Chen RK, Pan YH, Lee HL. Systematical evaluation of the effects of sample collection procedures on low-molecular-weight serum/plasma proteome profiling. Proteomics 6(10), 3189–3198 (2006).
  Medline CASGoogle Scholar
• 21 Ladenson JH, Tsai LM, Michael JM, Kessler G, Joist JH. Serum versus heparinized plasma for eighteen common chemistry tests: is serum the appropriate specimen? Am. J. Clin. Pathol. 62(4), 545–552 (1974).
  Medline CASGoogle Scholar
• 22 Miles RR, Roberts RF, Putnam AR, Roberts WL. Comparison of serum and heparinized plasma samples for measurement of chemistry. Clin. Chem. 50(9), 1704–1706 (2004).
  Medline CASGoogle Scholar
• 23 Liu L, Aa J, Wang G et al. Differences in metabolite profile between blood plasma and serum. Anal. Biochem. 406(2), 105–112 (2010).
  Medline CASGoogle Scholar
• 24 Drake SK, Bowen RA, Remaley AT, Hortin GL. Potential interferences from blood collection tubes in mass spectrometric analyses of serum polypeptides. Clin. Chem. 50(12), 2398–2401 (2004). • The authors found that polymer gel in a serum collection tube will shed in samples and be detected as peaks with a constant m/z interval.
  Medline CASGoogle Scholar
• 25 Pereira H, Martin JF, Joly C, Sébédio JL, Pujos-Guillot E. Development and validation of a UPLC/MS method for a nutritional metabolomic study of human plasma. Metabolomics 6(2), 207–218 (2010).
  CASGoogle Scholar
• 26 Bando K, Kawahara R, Kunimatsu T et al. Influences of biofluid sample collection and handling procedures on GC–MS based metabolomic studies. J. Biosci. Bioeng. 110(4), 491–499 (2010).
  Medline CASGoogle Scholar
• 27 Vuckovic D, Pawliszyn J. Systematic evaluation of solid-phase microextraction coatings for untargeted metabolomic profiling of biological fluids by liquid chromatography–mass spectrometry. Anal. Chem. 83(6), 1944–1954 (2011).
  Medline CASGoogle Scholar
• 28 Brown M, Dunn WB, Dobson P et al. Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics. Analyst 134(7), 1322–1332 (2009).
  Medline CASGoogle Scholar
• 29 Teahan O, Gamble S, Holmes E et al. Impact of analytical bias in metabonomic studies of human blood serum and plasma. Anal. Chem. 78(13), 4307–4318 (2006). • Compared the metabolomics profiling between serum and heparin plasma based on NMR spectroscopy. Further, the authors investigate the effect of serum clot condition and freeze–thawing circle.
  Medline CASGoogle Scholar
• 30 Teerlink T, Nijveldt RJ, de Jong S, van Leeuwen PA. Determination of arginine, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Anal. Biochem. 303(2), 131–137 (2002).
  Medline CASGoogle Scholar
• 31 Bruce SJ, Jonsson P, Antti H et al. Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: from extraction to data analysis. Anal. Biochem. 372(2), 237–249 (2008).
  Medline CASGoogle Scholar
• 32 Gika HG, Theodoridis GA, Wingate JE, Wilson ID. Within-day reproducibility of an HPLC–MS-based method for metabonomic analysis: application to human urine. J. Proteome Res. 6(8), 3291–3303 (2007).
  Medline CASGoogle Scholar
• 33 Kamleh MA, Ebbels TM, Spagou K, Masson P, Want EJ. Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies. Anal. Chem. 84(6), 2670–2677 (2012).
  Medline CASGoogle Scholar
• 34 van den Berg RA, Hoefsloot HC, Westerhuis JA, Smilde AK, van der Werf MJ. Centering, scaling and transformations: improving the biological information content of metabolomics data. BMC Genomics 7, 142–155 (2006).
  MedlineGoogle Scholar
• 35 Sumner LW, Amberg A, Barrett D et al. Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics 3(3), 211–221 (2007).
  Medline CASGoogle Scholar
• 36 Yin P, Peter A, Franken H et al. Preanalytical aspects and sample quality assessment in metabolomics studies of human blood. Clin. Chem. 59(5), 833–845 (2013).
  Medline CASGoogle Scholar
• 37 Banks RE, Stanley AJ, Cairns DA et al. Influences of blood sample processing on low-molecular-weight proteome identified by surface-enhanced laser desorption/ionization mass spectrometry. Clin. Chem. 51(9), 1637–1649 (2005).
  Medline CASGoogle Scholar
• 38 Bowen RA, Chan Y, Cohen J et al. Effect of blood collection tubes on total triiodothyronine and other laboratory assays. Clin. Chem. 51(2), 424–433 (2005).
  Medline CASGoogle Scholar
• 39 Karppi J, Akerman KK, Parviainen M. Suitability of collection tubes with separator gels for collecting and storing blood samples for therapeutic drug monitoring (TDM). Clin. Chem. Lab. Med. 38(4), 313–320 (2000).
  Medline CASGoogle Scholar
• 40 Jørgenrud B, Jäntti S, Mattila I et al. The influence of sample collection methodology and sample preprocessing on the blood metabolic profile. Bioanalysis 7(8), 991–1006 (2015). •• Investigated the differences among serum, citrate plasma and EDTA plasma on polar metabolites and lipids by GC × GC–TOF MS and ultra HPLC–TOF MS, respectively.
  CASGoogle Scholar
• 41 Mei H, Hsieh Y, Nardo C et al. Investigation of matrix effects in bioanalytical high performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery. Rapid Commun. Mass Spectrom. 17(1), 97–103 (2003).
  Medline CASGoogle Scholar
• 42 Hsu FF, Turk J. Characterization of phosphatidylethanolamine as a lithiated adduct by triple quadrupole tandem mass spectrometry with electrospray ionization. J. Am. Soc. Mass Spectrom. 35(5), 595–606 (2000).
  CASGoogle Scholar
• 43 Hsu FF, Turk J. Structural characterization of triacylglycerols as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisionally activated dissociation on a triple stage quadrupole instrument. J. Am. Soc. Mass Spectrom. 10(7), 587–599 (1999).
  Medline CASGoogle Scholar
• 44 Cubero Herrera L, Ramaley L, Potvin MA et al. A method for determining regioisomer abundances of polyunsaturated triacylglycerols in omega-3 enriched fish oils using reversed-phase liquid chromatography and triple-stage mass spectrometry. Food Chem. 139(1–4), 655–662 (2013).
  Medline CASGoogle Scholar