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The dextrans as vehicles for gene and drug delivery

    Shiyu Huang

    Chongqing Key Laboratory of Green Synthesis and Application, Active Carbohydrate Research Institute, Chongqing Normal University, Chongqing, 401331, China

    &
    Gangliang Huang

    *Author for correspondence:

    E-mail Address: huangdoctor226@163.com

    Chongqing Key Laboratory of Green Synthesis and Application, Active Carbohydrate Research Institute, Chongqing Normal University, Chongqing, 401331, China

    Published Online:https://doi.org/10.4155/fmc-2018-0586

    Dextran has become a hot research topic in drug vehicle material because of its biodegradable, nonspecific cell adhesion, resistance to protein adsorption, low price and ease of structural modification. The fate and changes of dextran in vivo are not fully understood. It is helpful to guide the design and modification of dextran drug vehicles to clarify the changes in the morphology, metabolism and function of drug targets. With the deep understanding of dextran and the emergence of new functional dextran derivatives, its application in nanodrug delivery systems will be more and more, clinically applicable delivery systems may also be available.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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