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Research Spotlight: Functionalized nanoparticles for future cardiovascular medicine

    Elsie Khai-Woon Toh

    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

    ,
    Ming-Yao Chang

    Department of Biomedical Engineering & Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan

    &
    Patrick CH Hsieh

    * Author for correspondence

    Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

    Published Online:https://doi.org/10.4155/tde.13.102

    All research investment has the goal of improving quality of life and health status. In recent years, the emerging technologies in nanomedicine research provide us a new frontier in the fight against human disease. By taking advantage of the unique physicochemical properties of nanoparticles (NPs), nanomedicine where drugs are blended into nanomaterials readily offers a wide range of applications in the tracing, diagnosis and treatment of disease. Although the application of therapeutic NPs is predominantly for cancer treatment, growing evidence has demonstrated the feasibility and potency of utilizing NPs for cardiovascular disease therapy. However, more consideration is required in this aspect due to limitations such as unfavorable particle retention in the contractile heart and the lack of cardiomyocyte markers for targeting.

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