References
- 1. Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury. Kidney Int. 93(6), 1330–1343 (2018).
- 2. . Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of SIR1 in diabetic Wistar fatty (fa/fa) rats: a model of Type 2 diabetes. Exp. Diabetes Res. 2011, 1–11 (2011).
- 3. Serum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: a randomized trial. Int. J. Cardiol. 227, 788–794 (2017).
- 4. . Exercise training upregulates SIRT1 to attenuate inflammation and metabolic dysfunction in kidney and liver of diabetic db/db mice. Nutr. Metab. (Lond.) 16, 22 (2019).
- 5. . Aerobic exercise training alleviates renal injury by interfering with mitochondrial function in Type-1 diabetic mice. Med. Sci. Monit. 24, 9081–9089 (2018).
- 6. Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK. Biochim. Biophys. Acta 1864(1), 115–125 (2018).
- 7. . Metformin ameliorates podocyte damage by restoring renal tissue nephrin expression in Type 2 diabetic rats. J. Diabetes 9(5), 510–517 (2017).
- 8. GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis. PLoS ONE 13(3), e0193473, 1–16 (2018).
- 9. Empagliflozin and progression of kidney disease in Type 2 diabetes. N. Engl. J. Med. 375(4), 323–334 (2016).
- 10. . Anti-fibrotic effect of losartan, an angiotensin II receptor blocker, is mediated through inhibition of ER stress via up-regulation of SIRT1, followed by induction of HO-1 and thioredoxin. Int. J. Mol. Sci. 18(2), pii:E305 (2017).
- 11. Olmesartan prevents microalbuminuria in db/db diabetic mice through inhibition of angiotensin II/p38/SIRT1-induced podocyte apoptosis. Kidney Blood Press. Res. 41(6), 848–864 (2016).
- 12. . Effect of resveratrol administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metab. Syndr. Relat. Disord. 12(10), 497–501 (2014).
- 13. . Resveratrol reduces albuminuria in diabetic nephropathy: a randomized double-blind placebo-controlled clinical trial. Diabetes Metab. 45(1), 53–59 (2019).
- 14. . Resveratrol-associated renal toxicity. Toxicol. Sci. 82(2), 614–619 (2004).
- 15. . Puerarin, isolated from Pueraria lobata (Willd.), protects against diabetic nephropathy by attenuating oxidative stress. Gene 591(2), 411–416 (2016).
- 16. The therapeutic effect and possible harm of puerarin for treatment of stage III diabetic nephropathy: a meta-analysis. Altern. Ther. Health Med. 21(1), 36–44 (2015).
- 17. . Formononetin attenuates kidney damage in Type 2 diabetic rats. Life Sci. 219, 109–121 (2019).
- 18. Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT-NF-kappaB p65 axis. Sci. Rep. 9(1), 323 (2019).
- 19. Small molecule activators of SIRT1 as therapeutics for the treatment of Type 2 diabetes. Nature 450(7170), 712–716 (2007).
- 20. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J. Biol. Chem. 285(11), 8340–8351 (2010).