Abstract
Sugar ligand molecules, such as mannose, galactose and glucose, can bind to drug-delivery systems, making them targeted. These glycosylation ligands have the advantages of nontoxicity, no immunogenicity, good biocompatibility and biodegradation. They can be widely used in glycosylation-modified drug-delivery systems. Herein, the targeting mechanisms, synthesis methods and targeting characteristics of glycosylation-modified drug-delivery systems were reviewed.
Papers of special note have been highlighted as: •• of considerable interest
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